The Ultimate Guide To https://www.ceesdekker.net

Wiki Article

Employing one-molecule optical and AFM imaging and power-spectroscopy tactics, we search for to unravel the mechanistic areas of the framework and dynamics of chromosomes. Our investigation passions contain:

Human Rad51 filaments on double- and solitary-stranded DNA: correlating regular and irregular kinds with recombination functionality.

Multicolor imaging with the bacterial nucleoid and cell division proteins with blue, orange, and close to-infrared fluorescent proteins

Sculpting nano-electrodes which has a transmission electron beam for electrical and geometrical characterization of nanoparticles.

This yielded a breakthrough. In only some months, we were in a position to evaluate transportation by means of an individual one-walled carbon nanotube. According to low-temperature experiments by an excellent PhD university student in my group, Sander Tans (now a valued colleague and professor at Delft University of Engineering with an active exploration lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes have been legitimate quantum wires with quite extended (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic behaviour.

Microbiology has only existed to get a century, due to the fact we started to review micro-organisms far more seriously. I thought nanobiology was an suitable phrase, since all molecular Organic suitable interactions take place for the nanoscale: a protein is a handful of nanometres in measurement, DNA is 2 nm thick.’

All parameters have been the exact same for every panel in this video, except for the Preliminary placement on the 6hb rod (demonstrated in blue) to the nanopore. Simulations that terminated early due to translocation from the rod with the pore are marked by a grey track record.

Researching DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.

You will help our writer matching process! In case you see any publications incorrectly attributed to this creator, please sign in and mark matches as right or incorrect.

Extremely amazing, but that wasn’t really the place my desire lay. I desired to pioneer and I experienced the sensation that was not probable, because the most exciting https://www.ceesdekker.net essential insights had previously been uncovered. But my industry had created a lot of exciting new resources to evaluate specific molecules. I made a decision that I desired to use this to biology, to take a look at it from the Actual physical point of view.’

In 1993 he was appointed as Affiliate Professor at Delft University of Technological know-how. Inside the mid-nineteen nineties Dekker and his group realized accomplishment with the invention of your electronic Homes of carbon nanotubes, the main single-molecule transistor along with other nanoscience.

1999, initially measurement from the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof for your new Luttinger description of interacting electrons in nanotubes

Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes

 Last but not least, I'll briefly sketch several of our Thoughts to explore the developing of synthetic cells, especially our very first methods to ascertain artificial cell division.